Ways of Treating IgA Nephropathies

Ways of Treating IgA Nephropathies

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Summary: Treatment options for IgA borstlist sj?lvh?ftande nephropathy (IgAN) must take into consideration the pathophysiology, namely the role of eicosanoids, angiotensin II and monocyte-macrophages releasing reactive oxygen species (ROS).Angiotensin converting enzyme inhibitors and early corticosteroid usage are prime therapies.Tonsillectomy should be considered.Other components of a therapeutic cocktail could be; (a) thromboxane antogonist, (b) leukotriene antagonist, (c) platelet activating factor antagonist, (d) an anti-oxidant and (e) an 2004 hyundai santa fe catalytic converter anti-fibrotic agent like pentoxyfylline.In the new millenium, there will be focus on anti-proliferative measures like platelets dependent growth factor aptamers.

For unusual cases with rapid progression, the use of FK-506 or mycophenolate mofetil can be considered.